Background and Objectives: Ovarian cancer is the leading cause of death among gynecological tumors.PD-1/PD-L1 immunoregulatory mechanism is activated in ovarian cancers.Lymphocyte infiltration is a significant factor that affects its expression.We analyzed the correlation between localization of lymphocytic infiltrate and PD-L1 expression in epithe
Abstract Transient receptor potential subfamily M member 7 (TRPM7), a mechanosensitive Ca2+ channel, plays a crucial role in intracellular Ca2+ homeostasis.However, it is currently unclear how cell mechanical cues control TRPM7 activity and its associated Ca2+ influx at plasma membrane microdomains.Using two different types of Ca2+ biosensors (Lyn-
Sarcoma development has been associated with genetics, irradiation, viral infections, and immunodeficiency.Reports of sarcomas arising in the setting of prior trauma, as in burn scars or Disposable Food Pan Liners fracture sites, are rare.We report a case of a leiomyosarcoma arising in an arm that had previously been replanted at the level of the e
The marabout is a mausoleum, a small architecture whose meaning transcends simple construction in favor of religious codes that through symbolic representation, implement the correspondence between the essence of human nature and the divine being.It is architecture with great symbolic value; its shapes the landscape skyline in Muslim World, especia